Finely tuned conformational dynamics regulate the protective function of the lncRNA MALAT1 triple helix

Nucleic acid triplexes may regulate many important biological processes. Persistent accumulation of the oncogenic 7-kb long noncoding RNA MALAT1 is dependent on an unusually long intramolecular triple helix. This triplex structure is positioned within a conserved ENE (element for nuclear expression)...

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Detalles Bibliográficos
Autores principales: Ageeli, Abeer A, McGovern-Gooch, Kayleigh R, Kaminska, Magdalena M, Baird, Nathan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379651/
https://www.ncbi.nlm.nih.gov/pubmed/30462290
http://dx.doi.org/10.1093/nar/gky1171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379651/
https://www.ncbi.nlm.nih.gov/pubmed/30462290
http://dx.doi.org/10.1093/nar/gky1171

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