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RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells

Nucleic acid–based assemblies that interact with each other and further communicate with the cellular machinery in a controlled manner represent a new class of reconfigurable materials that can overcome limitations of traditional biochemical approaches and improve the potential therapeutic utility o...

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Detalles Bibliográficos
Autores principales: Ke, Weina, Hong, Enping, Saito, Renata F, Rangel, Maria Cristina, Wang, Jian, Viard, Mathias, Richardson, Melina, Khisamutdinov, Emil F, Panigaj, Martin, Dokholyan, Nikolay V, Chammas, Roger, Dobrovolskaia, Marina A, Afonin, Kirill A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379676/
https://www.ncbi.nlm.nih.gov/pubmed/30517685
http://dx.doi.org/10.1093/nar/gky1215

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