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RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells
Nucleic acid–based assemblies that interact with each other and further communicate with the cellular machinery in a controlled manner represent a new class of reconfigurable materials that can overcome limitations of traditional biochemical approaches and improve the potential therapeutic utility o...
Autores principales: | Ke, Weina, Hong, Enping, Saito, Renata F, Rangel, Maria Cristina, Wang, Jian, Viard, Mathias, Richardson, Melina, Khisamutdinov, Emil F, Panigaj, Martin, Dokholyan, Nikolay V, Chammas, Roger, Dobrovolskaia, Marina A, Afonin, Kirill A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379676/ https://www.ncbi.nlm.nih.gov/pubmed/30517685 http://dx.doi.org/10.1093/nar/gky1215 |
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