The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs

Trans-splicing of trypanosomatid polycistronic transcripts produces polyadenylated monocistronic mRNAs modified to form the 5′ cap4 structure (m(7)Gpppm(3)(6,6,2′)Apm(2′)Apm(2′)Cpm(2)(3,2′)U). NMR and X-ray crystallography reveal that Leishmania has a unique type of N-terminally-extended cap-binding...

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Detalles Bibliográficos
Autores principales: dos Santos Rodrigues, Fabio Henrique, Firczuk, Helena, Breeze, Alexander L, Cameron, Alexander D, Walko, Martin, Wilson, Andrew J, Zanchin, Nilson I T, McCarthy, John E G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379680/
https://www.ncbi.nlm.nih.gov/pubmed/30476241
http://dx.doi.org/10.1093/nar/gky1187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379680/
https://www.ncbi.nlm.nih.gov/pubmed/30476241
http://dx.doi.org/10.1093/nar/gky1187

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