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Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases

APOBEC3 cytidine deaminases are largely known for their innate immune protection from viral infections. Recently, members of the family have been associated with a distinct mutational activity in some cancer types. We report a pan-tissue, pan-cancer analysis of RNA-seq data specific to the APOBEC3 g...

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Detalles Bibliográficos
Autores principales: Ng, Joseph C F, Quist, Jelmar, Grigoriadis, Anita, Malim, Michael H, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379723/
https://www.ncbi.nlm.nih.gov/pubmed/30624727
http://dx.doi.org/10.1093/nar/gky1316