Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome

Stevens - Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is a severe adverse drug reaction associated with involvement of skin and mucosal membranes, and carries significant risk of mortality and morbidity. Mucus membrane lesions usually involve the oral cavity, lips, bulbar conjunctiva...

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Autores principales: Jha, Ashish Kumar, Suchismita, Arya, Jha, Rajeev Kumar, Raj, Vikas Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379748/
https://www.ncbi.nlm.nih.gov/pubmed/30788030
http://dx.doi.org/10.4253/wjge.v11.i2.115
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author Jha, Ashish Kumar
Suchismita, Arya
Jha, Rajeev Kumar
Raj, Vikas Kumar
author_facet Jha, Ashish Kumar
Suchismita, Arya
Jha, Rajeev Kumar
Raj, Vikas Kumar
author_sort Jha, Ashish Kumar
collection PubMed
description Stevens - Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is a severe adverse drug reaction associated with involvement of skin and mucosal membranes, and carries significant risk of mortality and morbidity. Mucus membrane lesions usually involve the oral cavity, lips, bulbar conjunctiva and the anogenitalia. The oral/anal mucosa and liver are commonly involved in SJS or TEN. However, intestinal involvement is distinctly rare. We herein review the current literature regarding the gastrointestinal involvement in SJS or TEN. This review focuses mainly on the small bowel and colonic involvement in patients with SJS or TEN.
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spelling pubmed-63797482019-02-20 Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome Jha, Ashish Kumar Suchismita, Arya Jha, Rajeev Kumar Raj, Vikas Kumar World J Gastrointest Endosc Minireviews Stevens - Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) is a severe adverse drug reaction associated with involvement of skin and mucosal membranes, and carries significant risk of mortality and morbidity. Mucus membrane lesions usually involve the oral cavity, lips, bulbar conjunctiva and the anogenitalia. The oral/anal mucosa and liver are commonly involved in SJS or TEN. However, intestinal involvement is distinctly rare. We herein review the current literature regarding the gastrointestinal involvement in SJS or TEN. This review focuses mainly on the small bowel and colonic involvement in patients with SJS or TEN. Baishideng Publishing Group Inc 2019-02-16 2019-02-16 /pmc/articles/PMC6379748/ /pubmed/30788030 http://dx.doi.org/10.4253/wjge.v11.i2.115 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Jha, Ashish Kumar
Suchismita, Arya
Jha, Rajeev Kumar
Raj, Vikas Kumar
Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title_full Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title_fullStr Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title_full_unstemmed Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title_short Spectrum of gastrointestinal involvement in Stevens - Johnson syndrome
title_sort spectrum of gastrointestinal involvement in stevens - johnson syndrome
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379748/
https://www.ncbi.nlm.nih.gov/pubmed/30788030
http://dx.doi.org/10.4253/wjge.v11.i2.115
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