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Destabilization of spindle assembly checkpoint causes aneuploidy during meiosis II in murine post-ovulatory aged oocytes

Mammalian oocyte quality degrades over time after ovulation in vitro, which can cause fatal defects such as chromosomal aneuploidy. As various oocyte manipulations employed in assisted reproductive technology are time consuming, post-ovulatory aging is a serious problem to overcome in reproductive m...

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Detalles Bibliográficos
Autores principales:	SHIMOI, Gaku, TOMITA, Masaru, KATAOKA, Marino, KAMEYAMA, Yuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Society for Reproduction and Development 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379765/ https://www.ncbi.nlm.nih.gov/pubmed/30464155 http://dx.doi.org/10.1262/jrd.2018-056

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