Cargando…

Increased Transfection of the Easily Oxidizable GC-Rich DNA Fragments into the MCF7 Breast Cancer Cell

OBJECTIVE: Easily oxidizable GC-rich DNA (GC-DNA) fragments accumulate in the cell-free DNA (cfDNA) of patients with various diseases. The human oxidized DNA penetrates the MCF7 breast cancer cells and significantly changes their physiology. It can be assumed that readily oxidizable GC-DNA fragments...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kostyuk, Svetlana V., Mordkovich, Nadezhda N., Okorokova, Natalya A., Veiko, Vladimir P., Malinovskaya, Elena M., Ershova, Elizaveta S., Konkova, Marina S., Savinova, Ekaterina A., Borzikova, Maria A., Muzaffarova, Tatiana A., Porokhovnik, Lev N., Veiko, Nataly N., Kutsev, Serguey I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379852/ https://www.ncbi.nlm.nih.gov/pubmed/30867888 http://dx.doi.org/10.1155/2019/2348165

Ejemplares similares

Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells
por: Malinovskaya, Elena M., et al.
Publicado: (2019)

Extracellular DNA Containing (dG)n Motifs Penetrates into MCF7 Breast Cancer Cells, Induces the Adaptive Response, and Can Be Expressed
por: Kozhina, Ekaterina A., et al.
Publicado: (2019)

Copy Number of Human Ribosomal Genes With Aging: Unchanged Mean, but Narrowed Range and Decreased Variance in Elderly Group
por: Malinovskaya, Elena M., et al.
Publicado: (2018)

Copy Number Variation of Human Satellite III (1q12) With Aging
por: Ershova, Elizaveta S., et al.
Publicado: (2019)

Antipsychotics Affect Satellite III (1q12) Copy Number Variations in the Cultured Human Skin Fibroblasts
por: Ershova, Elizaveta S., et al.
Publicado: (2023)

1Q12 Loci Movement in the Interphase Nucleus Under the Action of ROS Is an Important Component of the Mechanism That Determines Copy Number Variation of Satellite III (1q12) in Health and Schizophrenia
por: Konkova, Marina Sergeevna, et al.
Publicado: (2020)

Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types
por: Kostyuk, Svetlana V., et al.
Publicado: (2018)

The Role of Human Satellite III (1q12) Copy Number Variation in the Adaptive Response during Aging, Stress, and Pathology: A Pendulum Model
por: Porokhovnik, Lev N., et al.
Publicado: (2021)

Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response
por: Sergeeva, V. A., et al.
Publicado: (2017)

Antioxidant Properties of Fullerene Derivatives Depend on Their Chemical Structure: A Study of Two Fullerene Derivatives on HELFs
por: Sergeeva, Vasilina, et al.
Publicado: (2019)

The Psychoemotional Stress-Induced Changes in the Abundance of SatIII (1q12) and Telomere Repeats, but Not Ribosomal DNA, in Human Leukocytes
por: Umriukhin, Pavel E., et al.
Publicado: (2022)

In Vitro Analysis of Biological Activity of Circulating Cell-Free DNA Isolated from Blood Plasma of Schizophrenic Patients and Healthy Controls—Part 2: Adaptive Response
por: Kostyuk, Svetlana V., et al.
Publicado: (2022)

Mesenchymal Stem Cells Early Response to Low-Dose Ionizing Radiation
por: Konkova, Marina, et al.
Publicado: (2020)

Effect of Low-Dose Ionizing Radiation on the Expression of Mitochondria-Related Genes in Human Mesenchymal Stem Cells
por: Kostyuk, Svetlana V., et al.
Publicado: (2021)

Mild cognitive impairment is associated with low copy number of ribosomal genes in the genomes of elderly people
por: Veiko, Natalia N., et al.
Publicado: (2022)

In Vitro Analysis of Biological Activity of Circulating Cell-Free DNA Isolated from Blood Plasma of Schizophrenic Patients and Healthy Controls
por: Ershova, Elizaveta S., et al.
Publicado: (2022)

Functionalized Fullerene Increases NF-κB Activity and Blocks Genotoxic Effect of Oxidative Stress in Serum-Starving Human Embryo Lung Diploid Fibroblasts
por: Ershova, E. S., et al.
Publicado: (2016)

Symmetric dimeric bisbenzimidazoles DBP(n) reduce methylation of RARB and PTEN while significantly increase methylation of rRNA genes in MCF-7 cancer cells
por: Kostyuk, Svetlana V., et al.
Publicado: (2018)

Oxidized Extracellular DNA as a Stress Signal in Human Cells
por: Ermakov, Aleksei V., et al.
Publicado: (2013)

The sacrificial role of easily oxidizable sites in the protection of DNA from damage
por: Kanvah, Sriram, et al.
Publicado: (2005)

NADPH-oxidase 4 gene over-expression in peripheral blood lymphocytes of the schizophrenia patients
por: Ershova, Elizaveta S., et al.
Publicado: (2022)

Ribosomal DNA Abundance in the Patient’s Genome as a Feasible Marker in Differential Diagnostics of Autism and Childhood-Onset Schizophrenia
por: Ershova, Elizaveta S., et al.
Publicado: (2022)

GC-Rich Extracellular DNA Induces Oxidative Stress, Double-Strand DNA Breaks, and DNA Damage Response in Human Adipose-Derived Mesenchymal Stem Cells
por: Kostyuk, Svetlana, et al.
Publicado: (2015)

The Phosphonate Derivative of C(60) Fullerene Induces Differentiation towards the Myogenic Lineage in Human Adipose-Derived Mesenchymal Stem Cells
por: Kostyuk, Svetlana V., et al.
Publicado: (2021)

Effects of Functionalized Fullerenes on ROS Homeostasis Determine Their Cytoprotective or Cytotoxic Properties
por: Kostyuk, Svetlana V., et al.
Publicado: (2020)

Oxidized Cell-Free DNA Role in the Antioxidant Defense Mechanisms under Stress
por: Filev, A. D., et al.
Publicado: (2019)

ROS-Induced DNA Damage Associates with Abundance of Mitochondrial DNA in White Blood Cells of the Untreated Schizophrenic Patients
por: Chestkov, I. V., et al.
Publicado: (2018)

Effects of Aqueous Dispersions of C(60), C(70) and Gd@C(82) Fullerenes on Genes Involved in Oxidative Stress and Anti-Inflammatory Pathways
por: Proskurnina, Elena V., et al.
Publicado: (2021)

Copy Number Variation of Satellite III (1q12) in Patients With Schizophrenia
por: Ershova, Elizaveta S., et al.
Publicado: (2019)

Accumulation of Circulating Cell-Free CpG-Enriched Ribosomal DNA Fragments on the Background of High Endonuclease Activity of Blood Plasma in Schizophrenic Patients
por: Ershova, E. S., et al.
Publicado: (2019)

Oxidized cell-free DNA as a stress-signaling factor activating the chronic inflammatory process in patients with autism spectrum disorders
por: Shmarina, Galina V., et al.
Publicado: (2020)

Association of NEF2L2 Rs35652124 Polymorphism with Nrf2 Induction and Genotoxic Stress Biomarkers in Autism
por: Porokhovnik, Lev N., et al.
Publicado: (2023)

An Exposure to the Oxidized DNA Enhances Both Instability of Genome and Survival in Cancer Cells
por: Kostyuk, Svetlana V., et al.
Publicado: (2013)

Oxidizability of Oils Recovered from Olive Seeds by Isothermal Calorimetry
por: Mosibo, Ornella Kongi, et al.
Publicado: (2022)

Amino acid profile and oxidizable vitamin content of Synsepalum dulcificum berry (miracle fruit) pulp
por: Njoku, Njideka E, et al.
Publicado: (2015)

Oxidizability assay of unfractionated plasma of patients’ with different plasma profile: a methodological study
por: Imam, Hasan, et al.
Publicado: (2014)

All-carbon multi-electrode array for real-time in vitro measurements of oxidizable neurotransmitters
por: Picollo, Federico, et al.
Publicado: (2016)

Mantle data imply a decline of oxidizable volcanic gases could have triggered the Great Oxidation
por: Kadoya, Shintaro, et al.
Publicado: (2020)

Fundamentals of laser-assisted micro- and nanotechnologies
por: Veiko, Vadim, et al.
Publicado: (2014)

High-resolution global population projections dataset developed with CMIP6 RCP and SSP scenarios for year 2010–2100
por: Olén, Niklas Boke, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u16slblt4msvmoe7bp30dqbvds