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Paroxysmal Nocturnal Hemoglobinuria with a Distinct Molecular Signature Diagnosed Ten Years after Allogenic Bone Marrow Transplantation for Acute Myeloid Leukemia

Paroxysmal nocturnal hemoglobinurea (PNH) is a rare disorder of complement regulation due to somatic mutation of PIGA (phosphatidylinositol glycan anchor) gene. We herewith report a case who developed a symptomatic PNH long after an allogenic marrow transplant. Some reasonable arguments concerning t...

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Detalles Bibliográficos
Autores principales: Santagostino, Alberto, Lombardi, Laura, Dine, Gerard, Hirsch, Pierre, Misra, Srimanta Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379860/
https://www.ncbi.nlm.nih.gov/pubmed/30867971
http://dx.doi.org/10.1155/2019/8928623

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