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Exosome-mediated targeted delivery of miR-210 for angiogenic therapy after cerebral ischemia in mice

BACKGROUND: Accumulating evidence shows that microRNA-210 (miR-210) holds great promise to improve angiogenesis for brain tissue repair after cerebral ischemia. However, safe and efficient delivery of miR-210 via intravenous administration is still a challenge. In the past decade, exosomes have emer...

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Detalles Bibliográficos
Autores principales: Zhang, Huixin, Wu, Jin, Wu, Jiahuan, Fan, Qi, Zhou, Jingchao, Wu, Junwen, Liu, Sichen, Zang, Jie, Ye, Jinhai, Xiao, Ming, Tian, Tian, Gao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379944/
https://www.ncbi.nlm.nih.gov/pubmed/30782171
http://dx.doi.org/10.1186/s12951-019-0461-7