Targeting PI3K in cancer: mechanisms and advances in clinical trials

Phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling is one of the most important intracellular pathways, which can be considered as a master regulator for cancer. Enormous efforts have been dedicated to the development of drugs targeting PI3K signaling, many of wh...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Nie, Ji, Ma, Xuelei, Wei, Yuquan, Peng, Yong, Wei, Xiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379961/
https://www.ncbi.nlm.nih.gov/pubmed/30782187
http://dx.doi.org/10.1186/s12943-019-0954-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379961/
https://www.ncbi.nlm.nih.gov/pubmed/30782187
http://dx.doi.org/10.1186/s12943-019-0954-x

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