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A functional variant alters binding of activating protein 1 regulating expression of FGF7 gene associated with chronic obstructive pulmonary disease

BACKGROUND: Genome-wide association studies (GWASs) of a large cohort of subjects with chronic obstructive pulmonary disease (COPD) have successfully identified multiple risk genes, including fibroblast growth factor 7 (FGF7). However, the underlying molecular mechanism influencing function of FGF7...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaomei, Guo, Yongxin, Yang, Jing, Niu, Jianlou, Du, Lina, Li, Haiyan, Li, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380023/
https://www.ncbi.nlm.nih.gov/pubmed/30777021
http://dx.doi.org/10.1186/s12881-019-0761-7