High-fat and high-glucose microenvironment decreases Runx2 and TAZ expression and inhibits bone regeneration in the mouse

BACKGROUND: Type 2 diabetes mellitus (T2DM) and hyperlipidemia are negatively related to bone regeneration. The aim of this study was to evaluate the effect of high-fat and high-glucose microenvironment on bone regeneration and to detect the expression of runt-related transcription factor 2 (Runx2)...

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Detalles Bibliográficos
Autores principales: Wu, Xuan, Zhang, Yunpeng, Xing, Yixiao, Zhao, Bin, Zhou, Cong, Wen, Yong, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380030/
https://www.ncbi.nlm.nih.gov/pubmed/30777111
http://dx.doi.org/10.1186/s13018-019-1084-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380030/
https://www.ncbi.nlm.nih.gov/pubmed/30777111
http://dx.doi.org/10.1186/s13018-019-1084-2

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