A randomized controlled trial of folic acid intervention in pregnancy highlights a putative methylation-regulated control element at ZFP57

BACKGROUND: Maternal blood folate concentrations during pregnancy have been previously linked with DNA methylation patterns, but this has been done predominantly through observational studies. We showed recently in an epigenetic analysis of the first randomized controlled trial (RCT) of folic acid s...

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Detalles Bibliográficos
Autores principales: Irwin, Rachelle E., Thursby, Sara-Jayne, Ondičová, Miroslava, Pentieva, Kristina, McNulty, Helene, Richmond, Rebecca C., Caffrey, Aoife, Lees-Murdock, Diane J., McLaughlin, Marian, Cassidy, Tony, Suderman, Matthew, Relton, Caroline L., Walsh, Colum P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380035/
https://www.ncbi.nlm.nih.gov/pubmed/30777123
http://dx.doi.org/10.1186/s13148-019-0618-0

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