Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines

Repair of a certain type of oxidative DNA damage leads to the release of phosphoglycolate, which is an inhibitor of triose phosphate isomerase and is predicted to indirectly inhibit phosphoglycerate mutase activity. Thus, we hypothesized that phosphoglycolate might play a role in a metabolic DNA dam...

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Detalles Bibliográficos
Autores principales: Gerin, Isabelle, Bury, Marina, Baldin, Francesca, Graff, Julie, Van Schaftingen, Emile, Bommer, Guido T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380167/
https://www.ncbi.nlm.nih.gov/pubmed/30670572
http://dx.doi.org/10.1042/BCJ20180435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380167/
https://www.ncbi.nlm.nih.gov/pubmed/30670572
http://dx.doi.org/10.1042/BCJ20180435

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