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Inhibition of multiple voltage-gated calcium channels may contribute to spinally mediated analgesia by epipregnanolone in a rat model of surgical paw incision

Voltage-activated calcium channels play an important role in excitability of sensory nociceptive neurons in acute and chronic pain models. We have previously shown that low-voltage-activated calcium channels, or T-type channels (T-channels), increase excitability of sensory neurons after surgical in...

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Detalles Bibliográficos
Autores principales: Joksimovic, Sonja Lj., Donald, Rebecca R., Park, Ji-Yong, Todorovic, Slobodan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380214/
https://www.ncbi.nlm.nih.gov/pubmed/30672394
http://dx.doi.org/10.1080/19336950.2018.1564420