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Correcting the R165K substitution in the first voltage-sensor of Ca(V)1.1 right-shifts the voltage-dependence of skeletal muscle calcium channel activation

The voltage-gated calcium channel Ca(V)1.1a primarily functions as voltage-sensor in skeletal muscle excitation-contraction (EC) coupling. In embryonic muscle the splice variant Ca(V)1.1e, which lacks exon 29, additionally function as a genuine L-type calcium channel. Because previous work in most l...

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Detalles Bibliográficos
Autores principales:	El Ghaleb, Yousra, Campiglio, Marta, Flucher, Bernhard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380215/ https://www.ncbi.nlm.nih.gov/pubmed/30638110 http://dx.doi.org/10.1080/19336950.2019.1568825

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