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Novel pipeline identifies new upstream ORFs and non-AUG initiating main ORFs with conserved amino acid sequences in the 5′ leader of mRNAs in Arabidopsis thaliana
Eukaryotic mRNAs contain a 5′ leader sequence preceding the main open reading frame (mORF) and, depending on the species, 20%–50% of eukaryotic mRNAs harbor an upstream ORF (uORF) in the 5′ leader. An unknown fraction of these uORFs encode sequence conserved peptides (conserved peptide uORFs, CPuORF...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380273/ https://www.ncbi.nlm.nih.gov/pubmed/30567971 http://dx.doi.org/10.1261/rna.067983.118 |