Cargando…

Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities

Antibodies provide immune protection by recognizing antigens of diverse chemical properties, but elucidating the amino acid sequence-function relationships underlying the specificity and affinity of antibody-antigen interactions remains challenging. We designed and constructed phage-displayed synthe...

Descripción completa

Detalles Bibliográficos
Autores principales: Jian, Jhih-Wei, Chen, Hong-Sen, Chiu, Yi-Kai, Peng, Hung-Pin, Tung, Chao-Ping, Chen, Ing-Chien, Yu, Chung-Ming, Tsou, Yueh-Liang, Kuo, Wei-Ying, Hsu, Hung-Ju, Yang, An-Suei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380391/
https://www.ncbi.nlm.nih.gov/pubmed/30526270
http://dx.doi.org/10.1080/19420862.2018.1550320