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Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities
Antibodies provide immune protection by recognizing antigens of diverse chemical properties, but elucidating the amino acid sequence-function relationships underlying the specificity and affinity of antibody-antigen interactions remains challenging. We designed and constructed phage-displayed synthe...
Autores principales: | Jian, Jhih-Wei, Chen, Hong-Sen, Chiu, Yi-Kai, Peng, Hung-Pin, Tung, Chao-Ping, Chen, Ing-Chien, Yu, Chung-Ming, Tsou, Yueh-Liang, Kuo, Wei-Ying, Hsu, Hung-Ju, Yang, An-Suei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380391/ https://www.ncbi.nlm.nih.gov/pubmed/30526270 http://dx.doi.org/10.1080/19420862.2018.1550320 |
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