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IL-10 polymorphisms +434T/C, +504G/T, and -2849C/T may predispose to tubulointersititial nephritis and uveitis in pediatric population

BACKGROUND: Tubulointerstitial nephritis (TIN) and uveitis syndrome (TINU) are likely to be autoimmune diseases. Based on previous studies, adults with isolated idiopathic uveitis have polymorphisms in interleukin 10 (IL-10) and tumor necrosis factor α (TNF-α) genes. We aimed to evaluate the presenc...

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Detalles Bibliográficos
Autores principales: Rytkönen, Sari, Ritari, Jarmo, Peräsaari, Juha, Saarela, Ville, Nuutinen, Matti, Jahnukainen, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380573/
https://www.ncbi.nlm.nih.gov/pubmed/30779760
http://dx.doi.org/10.1371/journal.pone.0211915

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