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Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study

BACKGROUND: There is significant heterogeneity in the clinical expression of structural brain abnormalities, including Alzheimer’s disease biomarkers. Some individuals preserve their memory despite the presence of risk factors or pathological brain changes, indicating resilience. We aimed to test wh...

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Detalles Bibliográficos
Autores principales: Topiwala, Anya, Suri, Sana, Allan, Charlotte, Valkanova, Vyara, Filippini, Nicola, Sexton, Claire E., Heise, Verena, Zsoldos, Enikő, Mahmood, Abda, Singh-Manoux, Archana, Mackay, Clare E., Kivimäki, Mika, Ebmeier, Klaus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380585/
https://www.ncbi.nlm.nih.gov/pubmed/30779761
http://dx.doi.org/10.1371/journal.pone.0211273