Cargando…

Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study

BACKGROUND: There is significant heterogeneity in the clinical expression of structural brain abnormalities, including Alzheimer’s disease biomarkers. Some individuals preserve their memory despite the presence of risk factors or pathological brain changes, indicating resilience. We aimed to test wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Topiwala, Anya, Suri, Sana, Allan, Charlotte, Valkanova, Vyara, Filippini, Nicola, Sexton, Claire E., Heise, Verena, Zsoldos, Enikő, Mahmood, Abda, Singh-Manoux, Archana, Mackay, Clare E., Kivimäki, Mika, Ebmeier, Klaus P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380585/ https://www.ncbi.nlm.nih.gov/pubmed/30779761 http://dx.doi.org/10.1371/journal.pone.0211273

Ejemplares similares

Resilience and MRI correlates of cognitive impairment in community-dwelling elders
por: Topiwala, Anya, et al.
Publicado: (2015)

Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study
por: Topiwala, Anya, et al.
Publicado: (2017)

Association of midlife stroke risk with structural brain integrity and memory performance at older ages: a longitudinal cohort study
por: Zsoldos, Enikő, et al.
Publicado: (2020)

Uncoupling protein 2 haplotype does not affect human brain structure and function in a sample of community-dwelling older adults
por: Heise, Verena, et al.
Publicado: (2017)

Association of Midlife Cardiovascular Risk Profiles With Cerebral Perfusion at Older Ages
por: Suri, Sana, et al.
Publicado: (2019)

Distinct resting-state functional connections associated with episodic and visuospatial memory in older adults
por: Suri, Sana, et al.
Publicado: (2017)

Association between gait and cognition in an elderly population based sample
por: Valkanova, Vyara, et al.
Publicado: (2018)

Associations Between Longitudinal Trajectories of Cognitive and Social Activities and Brain Health in Old Age
por: Anatürk, Melis, et al.
Publicado: (2020)

Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort()
por: Allan, Charlotte L., et al.
Publicado: (2016)

Corrigendum to: Sleep duration over 28 years, cognition, gray matter volume, and white matter microstructure: a prospective cohort study
por: Zitser, Jennifer, et al.
Publicado: (2020)

Sleep duration over 28 years, cognition, gray matter volume, and white matter microstructure: a prospective cohort study
por: Zitser, Jennifer, et al.
Publicado: (2020)

Allostatic load as a predictor of grey matter volume and white matter integrity in old age: The Whitehall II MRI study
por: Zsoldos, Enikő, et al.
Publicado: (2018)

Associations between self‐reported sleep quality and white matter in community‐dwelling older adults: A prospective cohort study
por: Sexton, Claire E., et al.
Publicado: (2017)

Effect of age and the APOE gene on metabolite concentrations in the posterior cingulate cortex
por: Suri, Sana, et al.
Publicado: (2017)

Associations between arterial stiffening and brain structure, perfusion, and cognition in the Whitehall II Imaging Sub-study: A retrospective cohort study
por: Suri, Sana, et al.
Publicado: (2020)

Associations between Mobility, Cognition, and Brain Structure in Healthy Older Adults
por: Demnitz, Naiara, et al.
Publicado: (2017)

White matter hyperintensities classified according to intensity and spatial location reveal specific associations with cognitive performance
por: Melazzini, Luca, et al.
Publicado: (2021)

Exploring variability in basal ganglia connectivity with functional MRI in healthy aging
por: Griffanti, Ludovica, et al.
Publicado: (2018)

Study protocol: the Whitehall II imaging sub-study
por: Filippini, Nicola, et al.
Publicado: (2014)

Association of Long-Term Diet Quality with Hippocampal Volume: Longitudinal Cohort Study
por: Akbaraly, Tasnime, et al.
Publicado: (2018)

Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging
por: Anatürk, Melis, et al.
Publicado: (2020)

Integrating large-scale neuroimaging research datasets: Harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets
por: Bordin, Valentina, et al.
Publicado: (2021)

Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study
por: Chouliaras, Leonidas, et al.
Publicado: (2018)

Inter- and intra-individual variation in brain structural-cognition relationships in aging
por: Patel, Raihaan, et al.
Publicado: (2022)

Association of cerebral small vessel disease burden with brain structure and cognitive and vascular risk trajectories in mid-to-late life
por: Jansen, Michelle G, et al.
Publicado: (2021)

Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
por: de Lange, Ann-Marie G., et al.
Publicado: (2020)

Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts
por: Anatürk, Melis, et al.
Publicado: (2023)

Alcohol consumption is associated with reduced creatine levels in the hippocampus of older adults
por: Demnitz, Naiara, et al.
Publicado: (2020)

A systematic review and meta-analysis of cross-sectional studies examining the relationship between mobility and cognition in healthy older adults
por: Demnitz, Naiara, et al.
Publicado: (2016)

Effect of Apolipoprotein E ε4 on the association between health behaviors and cognitive function in late midlife
por: Sabia, Séverine, et al.
Publicado: (2010)

Trajectories of Unhealthy Behaviors in Midlife and Risk of Disability at Older Ages in the Whitehall II Cohort Study
por: Artaud, Fanny, et al.
Publicado: (2016)

Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife
por: Singh-Manoux, Archana, et al.
Publicado: (2014)

Coronary heart disease and risk factors as predictors of trajectories of psychological distress from midlife to old age
por: Virtanen, Marianna, et al.
Publicado: (2017)

Association of walking speed in late midlife with mortality: results from the Whitehall II cohort study
por: Elbaz, Alexis, et al.
Publicado: (2012)

Midlife Risk Factors for Impaired Physical and Cognitive Functioning at Older Ages: A Cohort Study
por: Brunner, Eric J., et al.
Publicado: (2017)

Trajectories of the Framingham general cardiovascular risk profile in midlife and poor motor function later in life: The Whitehall II study()()
por: Elbaz, Alexis, et al.
Publicado: (2014)

Cumulative Associations Between Midlife Health Behaviors and Physical Functioning in Early Old Age: A 17-Year Prospective Cohort Study
por: Sabia, Séverine, et al.
Publicado: (2014)

Midlife contributors to socioeconomic differences in frailty during later life: a prospective cohort study
por: Brunner, Eric J, et al.
Publicado: (2018)

Socioeconomic and Psychosocial Adversity in Midlife and Depressive Symptoms Post Retirement: A 21-year Follow-up of the Whitehall II Study
por: Virtanen, Marianna, et al.
Publicado: (2015)

Metabolic Syndrome Over 10 Years and Cognitive Functioning in Late Midlife: The Whitehall II study
por: Akbaraly, Tasnime N., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_gcnee76jn8nph3n453o6emdf5h