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TRIM2, a novel member of the antiviral family, limits New World arenavirus entry

Tripartite motif (TRIM) proteins belong to a large family with many roles in host biology, including restricting virus infection. Here, we found that TRIM2, which has been implicated in cases of Charcot–Marie–Tooth disease (CMTD) in humans, acts by blocking hemorrhagic fever New World arenavirus (NW...

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Detalles Bibliográficos
Autores principales: Sarute, Nicolas, Ibrahim, Nouhou, Medegan Fagla, Bani, Lavanya, Madakasira, Cuevas, Christian, Stavrou, Spyridon, Otkiran-Clare, Guliz, Tyynismaa, Henna, Henao-Mejia, Jorge, Ross, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380604/
https://www.ncbi.nlm.nih.gov/pubmed/30726215
http://dx.doi.org/10.1371/journal.pbio.3000137

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