Cargando…
TRIM2, a novel member of the antiviral family, limits New World arenavirus entry
Tripartite motif (TRIM) proteins belong to a large family with many roles in host biology, including restricting virus infection. Here, we found that TRIM2, which has been implicated in cases of Charcot–Marie–Tooth disease (CMTD) in humans, acts by blocking hemorrhagic fever New World arenavirus (NW...
Autores principales: | Sarute, Nicolas, Ibrahim, Nouhou, Medegan Fagla, Bani, Lavanya, Madakasira, Cuevas, Christian, Stavrou, Spyridon, Otkiran-Clare, Guliz, Tyynismaa, Henna, Henao-Mejia, Jorge, Ross, Susan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380604/ https://www.ncbi.nlm.nih.gov/pubmed/30726215 http://dx.doi.org/10.1371/journal.pbio.3000137 |
Ejemplares similares
-
The board is set, the pieces are moving: Modulation of New World arenavirus entry by host proteins
por: Sarute, Nicolás, et al.
Publicado: (2021) -
The Curious Case of Arenavirus Entry, and Its Inhibition
por: Nunberg, Jack H., et al.
Publicado: (2012) -
Arenavirus reverse genetics: New approaches for the investigation of arenavirus biology and development of antiviral strategies
por: Emonet, Sebastien E., et al.
Publicado: (2011) -
Inhibition of Arenavirus Entry and Replication by the Cell-Intrinsic Restriction Factor ZMPSTE24 Is Enhanced by IFITM Antiviral Activity
por: Stott-Marshall, Robert J., et al.
Publicado: (2022) -
Host Cell Factors as Antiviral Targets in Arenavirus Infection
por: Linero, Florencia N., et al.
Publicado: (2012)