Cargando…

Intraperitoneal infusion of ex vivo-cultured allogeneic NK cells in recurrent ovarian carcinoma patients (a phase I study)

INTRODUCTION: Recurrent ovarian carcinoma has dismal prognosis, but control of disease and prolonged survival are possible in some patients. The estimated 5-year survival is 46% for all stages of ovarian cancer, and only 28% for metastasized disease. Notably, the majority of women with ovarian cance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hoogstad-van Evert, Janneke, Bekkers, Ruud, Ottevanger, Nelleke, Schaap, Nicolaas, Hobo, Willemijn, Jansen, Joop H., Massuger, Leon, Dolstra, Harry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380776/ https://www.ncbi.nlm.nih.gov/pubmed/30702598 http://dx.doi.org/10.1097/MD.0000000000014290

Ejemplares similares

Peritoneal NK cells are responsive to IL-15 and percentages are correlated with outcome in advanced ovarian cancer patients
por: Hoogstad-van Evert, Janneke S., et al.
Publicado: (2018)

Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice
por: Hoogstad-van Evert, Janneke S., et al.
Publicado: (2017)

TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer
por: Maas, Ralph Ja, et al.
Publicado: (2020)

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo
por: Thordardottir, Soley, et al.
Publicado: (2017)

CD34(+) progenitor-derived NK cell and gemcitabine combination therapy increases killing of ovarian cancer cells in NOD/SCID/IL2Rg(null) mice
por: Van der Meer, Jolien M.R., et al.
Publicado: (2021)

Cell composition and expansion strategy can reduce the beneficial effect of AKT-inhibition on functionality of CD8(+) T cells
por: Mousset, Charlotte M., et al.
Publicado: (2020)

A trispecific killer engager molecule against CLEC12A effectively induces NK cell mediated killing of AML cells
por: Arvindam, Upasana Sunil, et al.
Publicado: (2020)

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8(+) T cells for adoptive immunotherapy
por: Mousset, Charlotte M., et al.
Publicado: (2018)

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice
por: van der Waart, Anniek B., et al.
Publicado: (2015)

IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34(+) progenitor-derived NK cells
por: Van der Meer, J. M. R., et al.
Publicado: (2020)

Correction to: IL‑15 superagonist N‑803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor‑derived NK cells
por: Van der Meer, J. M. R., et al.
Publicado: (2021)

Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo
por: van Eck van der Sluijs, Jesper, et al.
Publicado: (2023)

Clinically applicable CD34(+)-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses
por: van Eck van der Sluijs, Jesper, et al.
Publicado: (2021)

Safety and feasibility study of ex vivo expanded allogeneic-NK cells infusion in patients with acute pneumonia caused by COVID-19
por: Ahmadvand, Mohammad, et al.
Publicado: (2023)

Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process
por: Spanholtz, Jan, et al.
Publicado: (2011)

Harnessing allogeneic NK cells: improving outcomes with tailored donor lymphocyte infusion
por: McCurdy, Shannon R.
Publicado: (2022)

The Promises of Natural Killer Cell Therapy in Endometriosis
por: Hoogstad-van Evert, Janneke, et al.
Publicado: (2022)

Infusion of Host-Derived Unlicensed NK Cells Improves Donor Engraftment in Non-Myeloablative Allogeneic Hematopoietic Cell Transplantation
por: Alvarez, Maite, et al.
Publicado: (2021)

Intrathecal CAR-NK cells infusion for isolated CNS relapse after allogeneic stem cell transplantation: case report
por: Yuan, Jing, et al.
Publicado: (2023)

Good manufacturing practice production of CD34(+) progenitor-derived NK cells for adoptive immunotherapy in acute myeloid leukemia
por: de Jonge, P. K. J. D., et al.
Publicado: (2023)

Exercise Programme in Endometrial Cancer; Protocol of the Feasibility and Acceptability Survivorship Trial (EPEC-FAST)
por: Smits, Anke, et al.
Publicado: (2015)

Current Perspectives on “Off-The-Shelf” Allogeneic NK and CAR-NK Cell Therapies
por: Heipertz, Erica L., et al.
Publicado: (2021)

Concurrent Detection of Circulating Minor Histocompatibility Antigen-Specific CD8(+) T Cells in SCT Recipients by Combinatorial Encoding MHC Multimers
por: Broen, Kelly, et al.
Publicado: (2011)

Long-term results and GvHD after prophylactic and preemptive donor lymphocyte infusion after allogeneic stem cell transplantation for acute leukemia
por: Schmid, Christoph, et al.
Publicado: (2021)

Systemic exposure to cisplatin and paclitaxel after intraperitoneal chemotherapy in ovarian cancer
por: de Jong, Loek A. W., et al.
Publicado: (2023)

Prolonged intraperitoneal infusion of 5-fluorouracil using a novel carrier solution.
por: Kerr, D. J., et al.
Publicado: (1996)

Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice
por: Silverstone, Peter H, et al.
Publicado: (2008)

Intraperitoneal Infusion of Mesenchymal Stem/Stromal Cells Prevents Experimental Autoimmune Uveitis in Mice
por: Oh, Joo Youn, et al.
Publicado: (2014)

Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis
por: Nam, Yoojun, et al.
Publicado: (2018)

The role of NK cells in HIV-1 protection: autologous, allogeneic or both?
por: Hens, Jef, et al.
Publicado: (2016)

One‐Step Method for Instant Generation of Advanced Allogeneic NK Cells
por: Lee, Daniel Y., et al.
Publicado: (2018)

Allogeneic Human Mesenchymal Stem Cell Infusions for Aging Frailty
por: Golpanian, Samuel, et al.
Publicado: (2017)

Ex-vivo expanded human NK cells mediate cytotoxicity and cytokine release against allogeneic cancer cell line by direct recognition and antibody directed cellular cytotoxicity: therapeutic potential use of NK cells for blood and solid tumors
por: Liacini, Abdelhamid, et al.
Publicado: (2014)

Delayed NK Cell Reconstitution and Reduced NK Activity Increased the Risks of CMV Disease in Allogeneic-Hematopoietic Stem Cell Transplantation
por: Park, Ki Hyun, et al.
Publicado: (2020)

Ex-vivo expanded human NK cells express activating receptors that mediate cytotoxicity of allogeneic and autologous cancer cell lines by direct recognition and antibody directed cellular cytotoxicity
por: Voskens, Caroline J, et al.
Publicado: (2010)

Allogeneic CD19-CAR-T cell infusion after allogeneic hematopoietic stem cell transplantation in B cell malignancies
por: Liu, Jun, et al.
Publicado: (2017)

Phase I Trial of Prophylactic Donor-Derived IL-2-Activated NK Cell Infusion after Allogeneic Hematopoietic Stem Cell Transplantation from a Matched Sibling Donor
por: Devillier, Raynier, et al.
Publicado: (2021)

High Log-Scale Expansion of Functional Human Natural Killer Cells from Umbilical Cord Blood CD34-Positive Cells for Adoptive Cancer Immunotherapy
por: Spanholtz, Jan, et al.
Publicado: (2010)

The relative risk of noncervical high‐risk human papillomavirus‐related (pre)malignancies after recurrent cervical intraepithelial neoplasia grade 3: A population‐based study
por: Loopik, Diede L., et al.
Publicado: (2019)

Anti-Tumor Potency of Short-Term Interleukin-15 Dendritic Cells Is Potentiated by In Situ Silencing of Programmed-Death Ligands
por: Versteven, Maarten, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_sh369oiaspegiqv3utnqtgmr7l