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Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center

Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectivel...

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Autores principales: Cho, Seong-Sik, Ju, Young-Su, Park, Hanwool, Kim, Young-Kug, Hwang, Shin, Choi, Seong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380783/
https://www.ncbi.nlm.nih.gov/pubmed/30702556
http://dx.doi.org/10.1097/MD.0000000000013979
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author Cho, Seong-Sik
Ju, Young-Su
Park, Hanwool
Kim, Young-Kug
Hwang, Shin
Choi, Seong-Soo
author_facet Cho, Seong-Sik
Ju, Young-Su
Park, Hanwool
Kim, Young-Kug
Hwang, Shin
Choi, Seong-Soo
author_sort Cho, Seong-Sik
collection PubMed
description Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectively analyzed 2007 adult recipients who underwent living donor liver transplantation in a single large center. The educational level was divided into three categories: middle school or lower, high school, and college or higher. The primary outcome was all-cause mortality after living donor liver transplantation. Stratified log-rank test and Cox proportional hazard model were employed for statistical analysis. The incidence rates of all-cause mortality were 23.85, 20.19, and 18.75 per 1000 person-year in recipients with middle school or lower, high school, and college or higher education groups, respectively. However, the gender-stratified log-rank test has not shown a statistically significant difference (P = .3107). In the unadjusted model, hazard ratio (HR) was 1.02 [95% confidence interval (CI) = 0.79–1.33] in high school and 1.23 (95% CI = 0.93–1.64) and in middle school or lower educational level, respectively; In the full adjusted model, the HR of high school was 0.98 (95% CI = 0.75–1.28) and the HR of middle school or lower was 1.01 (95% CI = 0.74–1.37). Although study population of this study is large, we could not find significant survival rate differences by the levels of education. Social selection and high compliance rate might contribute to this result.
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spelling pubmed-63807832019-03-04 Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center Cho, Seong-Sik Ju, Young-Su Park, Hanwool Kim, Young-Kug Hwang, Shin Choi, Seong-Soo Medicine (Baltimore) Research Article Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectively analyzed 2007 adult recipients who underwent living donor liver transplantation in a single large center. The educational level was divided into three categories: middle school or lower, high school, and college or higher. The primary outcome was all-cause mortality after living donor liver transplantation. Stratified log-rank test and Cox proportional hazard model were employed for statistical analysis. The incidence rates of all-cause mortality were 23.85, 20.19, and 18.75 per 1000 person-year in recipients with middle school or lower, high school, and college or higher education groups, respectively. However, the gender-stratified log-rank test has not shown a statistically significant difference (P = .3107). In the unadjusted model, hazard ratio (HR) was 1.02 [95% confidence interval (CI) = 0.79–1.33] in high school and 1.23 (95% CI = 0.93–1.64) and in middle school or lower educational level, respectively; In the full adjusted model, the HR of high school was 0.98 (95% CI = 0.75–1.28) and the HR of middle school or lower was 1.01 (95% CI = 0.74–1.37). Although study population of this study is large, we could not find significant survival rate differences by the levels of education. Social selection and high compliance rate might contribute to this result. Wolters Kluwer Health 2019-02-01 /pmc/articles/PMC6380783/ /pubmed/30702556 http://dx.doi.org/10.1097/MD.0000000000013979 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Research Article
Cho, Seong-Sik
Ju, Young-Su
Park, Hanwool
Kim, Young-Kug
Hwang, Shin
Choi, Seong-Soo
Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title_full Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title_fullStr Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title_full_unstemmed Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title_short Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
title_sort impact of educational levels on survival rate: a cohort study of 2007 living donor liver transplant recipients at a single large center
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380783/
https://www.ncbi.nlm.nih.gov/pubmed/30702556
http://dx.doi.org/10.1097/MD.0000000000013979
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