Cargando…
Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center
Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectivel...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380783/ https://www.ncbi.nlm.nih.gov/pubmed/30702556 http://dx.doi.org/10.1097/MD.0000000000013979 |
_version_ | 1783396360652849152 |
---|---|
author | Cho, Seong-Sik Ju, Young-Su Park, Hanwool Kim, Young-Kug Hwang, Shin Choi, Seong-Soo |
author_facet | Cho, Seong-Sik Ju, Young-Su Park, Hanwool Kim, Young-Kug Hwang, Shin Choi, Seong-Soo |
author_sort | Cho, Seong-Sik |
collection | PubMed |
description | Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectively analyzed 2007 adult recipients who underwent living donor liver transplantation in a single large center. The educational level was divided into three categories: middle school or lower, high school, and college or higher. The primary outcome was all-cause mortality after living donor liver transplantation. Stratified log-rank test and Cox proportional hazard model were employed for statistical analysis. The incidence rates of all-cause mortality were 23.85, 20.19, and 18.75 per 1000 person-year in recipients with middle school or lower, high school, and college or higher education groups, respectively. However, the gender-stratified log-rank test has not shown a statistically significant difference (P = .3107). In the unadjusted model, hazard ratio (HR) was 1.02 [95% confidence interval (CI) = 0.79–1.33] in high school and 1.23 (95% CI = 0.93–1.64) and in middle school or lower educational level, respectively; In the full adjusted model, the HR of high school was 0.98 (95% CI = 0.75–1.28) and the HR of middle school or lower was 1.01 (95% CI = 0.74–1.37). Although study population of this study is large, we could not find significant survival rate differences by the levels of education. Social selection and high compliance rate might contribute to this result. |
format | Online Article Text |
id | pubmed-6380783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-63807832019-03-04 Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center Cho, Seong-Sik Ju, Young-Su Park, Hanwool Kim, Young-Kug Hwang, Shin Choi, Seong-Soo Medicine (Baltimore) Research Article Among living donor liver transplantation recipients, the impact of educational levels on survival has rarely explored. Thus, the purpose of study is to analyze the survival rate differences across educational levels among recipients who underwent living donor liver transplantation. We retrospectively analyzed 2007 adult recipients who underwent living donor liver transplantation in a single large center. The educational level was divided into three categories: middle school or lower, high school, and college or higher. The primary outcome was all-cause mortality after living donor liver transplantation. Stratified log-rank test and Cox proportional hazard model were employed for statistical analysis. The incidence rates of all-cause mortality were 23.85, 20.19, and 18.75 per 1000 person-year in recipients with middle school or lower, high school, and college or higher education groups, respectively. However, the gender-stratified log-rank test has not shown a statistically significant difference (P = .3107). In the unadjusted model, hazard ratio (HR) was 1.02 [95% confidence interval (CI) = 0.79–1.33] in high school and 1.23 (95% CI = 0.93–1.64) and in middle school or lower educational level, respectively; In the full adjusted model, the HR of high school was 0.98 (95% CI = 0.75–1.28) and the HR of middle school or lower was 1.01 (95% CI = 0.74–1.37). Although study population of this study is large, we could not find significant survival rate differences by the levels of education. Social selection and high compliance rate might contribute to this result. Wolters Kluwer Health 2019-02-01 /pmc/articles/PMC6380783/ /pubmed/30702556 http://dx.doi.org/10.1097/MD.0000000000013979 Text en Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 |
spellingShingle | Research Article Cho, Seong-Sik Ju, Young-Su Park, Hanwool Kim, Young-Kug Hwang, Shin Choi, Seong-Soo Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title | Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title_full | Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title_fullStr | Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title_full_unstemmed | Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title_short | Impact of educational levels on survival rate: A cohort study of 2007 living donor liver transplant recipients at a single large center |
title_sort | impact of educational levels on survival rate: a cohort study of 2007 living donor liver transplant recipients at a single large center |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380783/ https://www.ncbi.nlm.nih.gov/pubmed/30702556 http://dx.doi.org/10.1097/MD.0000000000013979 |
work_keys_str_mv | AT choseongsik impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter AT juyoungsu impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter AT parkhanwool impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter AT kimyoungkug impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter AT hwangshin impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter AT choiseongsoo impactofeducationallevelsonsurvivalrateacohortstudyof2007livingdonorlivertransplantrecipientsatasinglelargecenter |