Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

The vertebrate eye originates from the eye field, a domain of cells specified by a small number of transcription factors. In this study, we show that Tcf7l1a is one such transcription factor that acts cell-autonomously to specify the eye field in zebrafish. Despite the much-reduced eye field in tcf7...

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Detalles Bibliográficos
Autores principales: Young, Rodrigo M, Hawkins, Thomas A, Cavodeassi, Florencia, Stickney, Heather L, Schwarz, Quenten, Lawrence, Lisa M, Wierzbicki, Claudia, Cheng, Bowie YL, Luo, Jingyuan, Ambrosio, Elizabeth Mayela, Klosner, Allison, Sealy, Ian M, Rowell, Jasmine, Trivedi, Chintan A, Bianco, Isaac H, Allende, Miguel L, Busch-Nentwich, Elisabeth M, Gestri, Gaia, Wilson, Stephen W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380838/
https://www.ncbi.nlm.nih.gov/pubmed/30777146
http://dx.doi.org/10.7554/eLife.40093

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