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Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women

Per- and polyfluoroalkyl substances (PFASs) are used in a wide range of consumer products for their water- and grease-resistant properties, but few studies have explored this exposure route. We used multiple regression to investigate associations between six self-reported behaviors hypothesized to i...

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Autores principales: Boronow, Katherine E., Brody, Julia Green, Schaider, Laurel A., Peaslee, Graham F., Havas, Laurie, Cohn, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380931/
https://www.ncbi.nlm.nih.gov/pubmed/30622332
http://dx.doi.org/10.1038/s41370-018-0109-y
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author Boronow, Katherine E.
Brody, Julia Green
Schaider, Laurel A.
Peaslee, Graham F.
Havas, Laurie
Cohn, Barbara A.
author_facet Boronow, Katherine E.
Brody, Julia Green
Schaider, Laurel A.
Peaslee, Graham F.
Havas, Laurie
Cohn, Barbara A.
author_sort Boronow, Katherine E.
collection PubMed
description Per- and polyfluoroalkyl substances (PFASs) are used in a wide range of consumer products for their water- and grease-resistant properties, but few studies have explored this exposure route. We used multiple regression to investigate associations between six self-reported behaviors hypothesized to influence PFAS exposure and serum concentrations of six PFAS chemicals in 178 middle-aged women enrolled in the Child Health and Development Studies, about half of whom are African American. Blood samples were collected in 2010–2013, and participants were interviewed about behavior in 2015–2016. Results showed that African American women had lower levels of perfluorooctanoic acid (PFOA) and perfluorohexanesulfonic acid (PFHxS) compared with non-Hispanic white women. In African Americans, but not others, frequent consumption of prepared food in coated cardboard containers was associated with higher levels of four PFASs. Flossing with Oral-B Glide, having stain-resistant carpet or furniture, and living in a city served by a PFAS-contaminated water supply were also associated with higher levels of some PFASs. Product testing using particle-induced γ-ray emission (PIGE) spectroscopy confirmed that Oral-B Glide and competitor flosses contained detectable fluorine. Despite the delay between blood collection and interview, these results strengthen the evidence for exposure to PFASs from food packaging and implicate exposure from polytetrafluoroethylene (PTFE)-based dental floss for the first time.
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spelling pubmed-63809312019-07-08 Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women Boronow, Katherine E. Brody, Julia Green Schaider, Laurel A. Peaslee, Graham F. Havas, Laurie Cohn, Barbara A. J Expo Sci Environ Epidemiol Article Per- and polyfluoroalkyl substances (PFASs) are used in a wide range of consumer products for their water- and grease-resistant properties, but few studies have explored this exposure route. We used multiple regression to investigate associations between six self-reported behaviors hypothesized to influence PFAS exposure and serum concentrations of six PFAS chemicals in 178 middle-aged women enrolled in the Child Health and Development Studies, about half of whom are African American. Blood samples were collected in 2010–2013, and participants were interviewed about behavior in 2015–2016. Results showed that African American women had lower levels of perfluorooctanoic acid (PFOA) and perfluorohexanesulfonic acid (PFHxS) compared with non-Hispanic white women. In African Americans, but not others, frequent consumption of prepared food in coated cardboard containers was associated with higher levels of four PFASs. Flossing with Oral-B Glide, having stain-resistant carpet or furniture, and living in a city served by a PFAS-contaminated water supply were also associated with higher levels of some PFASs. Product testing using particle-induced γ-ray emission (PIGE) spectroscopy confirmed that Oral-B Glide and competitor flosses contained detectable fluorine. Despite the delay between blood collection and interview, these results strengthen the evidence for exposure to PFASs from food packaging and implicate exposure from polytetrafluoroethylene (PTFE)-based dental floss for the first time. Nature Publishing Group US 2019-01-08 2019 /pmc/articles/PMC6380931/ /pubmed/30622332 http://dx.doi.org/10.1038/s41370-018-0109-y Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Boronow, Katherine E.
Brody, Julia Green
Schaider, Laurel A.
Peaslee, Graham F.
Havas, Laurie
Cohn, Barbara A.
Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title_full Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title_fullStr Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title_full_unstemmed Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title_short Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women
title_sort serum concentrations of pfass and exposure-related behaviors in african american and non-hispanic white women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380931/
https://www.ncbi.nlm.nih.gov/pubmed/30622332
http://dx.doi.org/10.1038/s41370-018-0109-y
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