Cargando…

Exposure to Sub-inhibitory Concentrations of the Chemosensitizer 1-(1-Naphthylmethyl)-Piperazine Creates Membrane Destabilization in Multi-Drug Resistant Klebsiella pneumoniae

Antimicrobial efflux is one of the important mechanisms causing multi-drug resistance (MDR) in bacteria. Chemosensitizers like 1-(1-naphthylmethyl)-piperazine (NMP) can inhibit an efflux pump and therefore can overcome MDR. However, secondary effects of NMP other than efflux pump inhibition are rare...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anes, João, Sivasankaran, Sathesh K., Muthappa, Dechamma M., Fanning, Séamus, Srikumar, Shabarinath
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381021/ https://www.ncbi.nlm.nih.gov/pubmed/30814979 http://dx.doi.org/10.3389/fmicb.2019.00092

Ejemplares similares

Silver Nanoparticles Induce a Triclosan-Like Antibacterial Action Mechanism in Multi-Drug Resistant Klebsiella pneumoniae
por: Pareek, Vikram, et al.
Publicado: (2021)

Analysis of the Oxidative Stress Regulon Identifies soxS as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae
por: Anes, João, et al.
Publicado: (2021)

(1-Naphthylmethyl)ammonium chloride
por: Salimi, Ali R., et al.
Publicado: (2010)

A Review on the Applications of Next Generation Sequencing Technologies as Applied to Food-Related Microbiome Studies
por: Cao, Yu, et al.
Publicado: (2017)

Exploring the Genome and Phenotype of Multi-Drug Resistant Klebsiella pneumoniae of Clinical Origin
por: Anes, João, et al.
Publicado: (2017)

Flow Cytometric and 16S Sequencing Methodologies for Monitoring the Physiological Status of the Microbiome in Powdered Infant Formula Production
por: Anvarian, Amir H. P., et al.
Publicado: (2016)

Bis(2-naphthylmethyl)diphenylsilane
por: Monroe, Thomas Blake, et al.
Publicado: (2009)

RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium
por: Srikumar, Shabarinath, et al.
Publicado: (2015)

Comparative genomic insights into Yersinia hibernica – a commonly misidentified Yersinia enterocolitica-like organism
por: Nguyen, Scott Van, et al.
Publicado: (2020)

Crystal structure of piperazine-1,4-diium bis(4-aminobenzenesulfonate)
por: Kumar, K. Sathesh, et al.
Publicado: (2015)

Synthesis of monophosphorylated lipid A precursors using 2-naphthylmethyl ether as a protecting group
por: Xue, Jundi, et al.
Publicado: (2020)

Draft genome sequences of Salmonella Oslo isolated from seafood and its laboratory generated auxotrophic mutant
por: Jazeela, Kadeeja, et al.
Publicado: (2020)

1-Butyl-3-(1-naphthylmethyl)benzimidazolium hemi{di-μ-iodido-bis[diiodidomercurate(II)]} dimethyl sulfoxide monosolvate
por: Wang, Zhi-Qiang, et al.
Publicado: (2009)

Increased Virulence of Bloodstream Over Peripheral Isolates of P. aeruginosa Identified Through Post-transcriptional Regulation of Virulence Factors
por: Hickey, Caitríona, et al.
Publicado: (2018)

Dichlorido[1-(1-naphthylmethyl)-3-(2-pyridyl)-1H-pyrazole-κ(2) N (2),N (3)]palladium(II)
por: Liu, Chun-Sen, et al.
Publicado: (2007)

The ins and outs of RND efflux pumps in Escherichia coli
por: Anes, João, et al.
Publicado: (2015)

1,4-Dibenzylpiperazine
por: Zhang, Meng, et al.
Publicado: (2010)

Three-dimensional network in piperazine-1,4-diium–picrate–piperazine (1/2/1)
por: Wang, Zhong-Long, et al.
Publicado: (2008)

Draft Genome Sequences of Three Novel Acinetobacter Isolates from an Irish Commercial Pig Farm
por: Pereira do Vale, Ana, et al.
Publicado: (2019)

[3,3′-Bis(1-naphthylmethyl)-1,1′-(2,2′-oxydiethylene)bis(imidazol-2-ylidene)]mercury(II) bis(hexafluoridophosphate) acetonitrile solvate
por: Guo, Wen-Yan, et al.
Publicado: (2009)

Multidrug-Resistant Escherichia coli in Bovine Animals, Europe
por: Brennan, Evan, et al.
Publicado: (2016)

ATF4 destabilizes RET through nonclassical GRP78 inhibition to enhance chemosensitivity to bortezomib in human osteosarcoma
por: Luo, Jie, et al.
Publicado: (2019)

Piperazine-1,4-diium diacetate
por: Hou, Shao-Gang
Publicado: (2011)

CKD-712, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, Inhibits the NF-κB Activation and Augments Akt Activation during TLR4 Signaling
por: Lee, Jeonggi, et al.
Publicado: (2011)

Sesquiterpene Alcohol Cedrol Chemosensitizes Human Cancer Cells and Suppresses Cell Proliferation by Destabilizing Plasma Membrane Lipid Rafts
por: Mishra, Siddhartha Kumar, et al.
Publicado: (2021)

1-Methylpiperazine-1,4-diium dipicrate
por: Dutkiewicz, Grzegorz, et al.
Publicado: (2011)

Mild Method for 2-Naphthylmethyl Ether Protecting Group Removal Using a Combination of 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and β-Pinene
por: Lloyd, Dina, et al.
Publicado: (2017)

Investigation of the Anti-Methicillin-Resistant Staphylococcus aureus Activity of (+)-Tanikolide- and (+)-Malyngolide-Based Analogues Prepared by Asymmetric Synthesis
por: Breheny, Joseph, et al.
Publicado: (2021)

(±)-2-Methylpiperazin-1-ium perchlorate
por: Peng, Cong-Hu
Publicado: (2010)

4-Nitrophenol–piperazine (2/1)
por: Nagapandiselvi, Perumal, et al.
Publicado: (2013)

Reference Transcriptomes of Porcine Peripheral Immune Cells Created Through Bulk and Single-Cell RNA Sequencing
por: Herrera-Uribe, Juber, et al.
Publicado: (2021)

Piperazine-1,4-diium naphthalene-1,5-disulfonate
por: Wei, Bin
Publicado: (2011)

New 7-[4-(4-(un)Substituted)piperazine-1-carbonyl]-piperazin-1-yl] Derivatives of Fluoroquinolone: Synthesis and Antimicrobial Evaluation
por: Chen, Po-Ting, et al.
Publicado: (2013)

Inhibitory Receptor Signaling Destabilizes Immunological Synapse Formation in Primary NK Cells
por: Abeyweera, Thushara P., et al.
Publicado: (2013)

The Secretion of Toxins and Other Exoproteins of Cronobacter: Role in Virulence, Adaption, and Persistence
por: Jang, Hyein, et al.
Publicado: (2020)

6-Bromo-2-naphthol–piperazine (2/1)
por: Tian, Yan, et al.
Publicado: (2008)

7-Chloro-4-(piperazin-1-yl)quinoline
por: Kulkarni, Amol A., et al.
Publicado: (2012)

4-Phenylpiperazin-1-ium dihydrogen phosphate
por: Essid, Manel, et al.
Publicado: (2010)

Piperazine-1,4-diium bis(perchlorate) dihydrate
por: Peng, Cong-hu
Publicado: (2010)

Crystal structures of 4-(pyrimidin-2-yl)piperazin-1-ium chloride and 4-(pyrimidin-2-yl)piperazin-1-ium nitrate
por: Yamuna, Thammarse S., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fvuh9d7ljcs3pip7lajjpufnhq