Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice

Hemophagocytic lymphohistiocytosis (HLH) has recently been increasingly reported as an important complication after stem cell transplantation, in line with the increase in the number of HLA-mismatched transplantation. Although previous clinical studies have shown an elevation of inflammatory cytokin...

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Detalles Bibliográficos
Autores principales: Yoshihara, Satoshi, Li, Yuying, Xia, Jinxing, Danzl, Nichole, Sykes, Megan, Yang, Yong-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381030/
https://www.ncbi.nlm.nih.gov/pubmed/30814997
http://dx.doi.org/10.3389/fimmu.2019.00186

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