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Increases in a Pro-inflammatory Chemokine, MCP-1, Are Related to Decreases in Memory Over Time

Objective: To determine the longitudinal relationship between monocyte chemotactic protein 1 (MCP-1)/CCL2 and memory function in older adults. Methods: We examined longitudinal plasma MCP-1/CCL2 levels and a longitudinal verbal memory measure (CVLT-II 20’ recall) in a sample of 399 asymptomatic olde...

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Detalles Bibliográficos
Autores principales: Bettcher, Brianne M., Neuhaus, John, Wynn, Matthew J., Elahi, Fanny M., Casaletto, Kaitlin B., Saloner, Rowan, Fitch, Ryan, Karydas, Anna, Kramer, Joel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381047/
https://www.ncbi.nlm.nih.gov/pubmed/30814948
http://dx.doi.org/10.3389/fnagi.2019.00025