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Hyperosmotic stress induces cell-dependent aggregation of α-synuclein

The aggregation of alpha-synuclein (α-syn) is a pathological feature of a number of neurodegenerative conditions, including Parkinson’s disease. Genetic mutations, abnormal protein synthesis, environmental stress, and aging have all been implicated as causative factors in this process. The importanc...

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Detalles Bibliográficos
Autores principales: Fragniere, Alexandra M. C., Stott, Simon R. W., Fazal, Shaline V., Andreasen, Maria, Scott, Kirsten, Barker, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381101/
https://www.ncbi.nlm.nih.gov/pubmed/30783136
http://dx.doi.org/10.1038/s41598-018-38296-7