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Defining a critical period in calvarial development for Hedgehog pathway antagonist-induced frontal bone dysplasia in mice
The Hedgehog (Hh) signalling pathway is essential for cellular proliferation and differentiation during embryonic development. Gain and loss of function of Hh signalling are known to result in an array of craniofacial malformations. To determine the critical period for Hh pathway antagonist-induced...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381108/ https://www.ncbi.nlm.nih.gov/pubmed/30783111 http://dx.doi.org/10.1038/s41368-018-0040-z |