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Defining a critical period in calvarial development for Hedgehog pathway antagonist-induced frontal bone dysplasia in mice

The Hedgehog (Hh) signalling pathway is essential for cellular proliferation and differentiation during embryonic development. Gain and loss of function of Hh signalling are known to result in an array of craniofacial malformations. To determine the critical period for Hh pathway antagonist-induced...

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Detalles Bibliográficos
Autores principales: Jiang, Yuanjing, Zhang, Shixian, Mao, Chuanqing, Lai, Yongzhen, Wu, Di, Zhao, Hu, Liao, Caiyu, Chen, Weihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381108/
https://www.ncbi.nlm.nih.gov/pubmed/30783111
http://dx.doi.org/10.1038/s41368-018-0040-z