Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer

Oxaliplatin is important for the clinical treatment of colorectal cancer and other gastrointestinal malignancies, but tumour resistance is limiting. Several oxaliplatin transporters were previously identified but their relative contributions to determining oxaliplatin tumour responses and gastrointe...

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Detalles Bibliográficos
Autores principales: Myint, Khine, Biswas, Riya, Li, Yan, Jong, Nancy, Jamieson, Stephen, Liu, Johnson, Han, Catherine, Squire, Christopher, Merien, Fabrice, Lu, Jun, Nakanishi, Takeo, Tamai, Ikumi, McKeage, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381153/
https://www.ncbi.nlm.nih.gov/pubmed/30783141
http://dx.doi.org/10.1038/s41598-019-38667-8

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