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Anoctamin-4 is a bona fide Ca(2+)-dependent non-selective cation channel

Changes in cell function occur by specific patterns of intracellular Ca(2+), activating Ca(2+)-sensitive proteins. The anoctamin (TMEM16) protein family has Ca(2+)-dependent ion channel activity, which provides transmembrane ion transport, and/or Ca(2+)-dependent phosphatidyl-scramblase activity. Us...

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Detalles Bibliográficos
Autores principales: Reichhart, Nadine, Schöberl, Simon, Keckeis, Susanne, Alfaar, Ahmad S., Roubeix, Christophe, Cordes, Magdalena, Crespo-Garcia, Sergio, Haeckel, Akvile, Kociok, Norbert, Föckler, Renate, Fels, Gabriele, Mataruga, Anja, Rauh, Robert, Milenkovic, Vladimir M., Zühlke, Kerstin, Klussmann, Enno, Schellenberger, Eyk, Strauß, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381168/
https://www.ncbi.nlm.nih.gov/pubmed/30783137
http://dx.doi.org/10.1038/s41598-018-37287-y