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Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia

Dysregulation of the ubiquitin proteasome system (UPS) has been linked to schizophrenia but it is not clear if this dysregulation is detectable in both brain and blood. We examined free mono-ubiquitin, ubiquitinated proteins, catalytic ubiquitination, and proteasome activities in frozen postmortem O...

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Detalles Bibliográficos
Autores principales: Bousman, Chad A., Luza, Sandra, Mancuso, Serafino G., Kang, Dali, Opazo, Carlos M., Mostaid, Md. Shaki, Cropley, Vanessa, McGorry, Patrick, Shannon Weickert, Cynthia, Pantelis, Christos, Bush, Ashley I., Everall, Ian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381171/
https://www.ncbi.nlm.nih.gov/pubmed/30783160
http://dx.doi.org/10.1038/s41598-019-38490-1