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Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia
Dysregulation of the ubiquitin proteasome system (UPS) has been linked to schizophrenia but it is not clear if this dysregulation is detectable in both brain and blood. We examined free mono-ubiquitin, ubiquitinated proteins, catalytic ubiquitination, and proteasome activities in frozen postmortem O...
Autores principales: | Bousman, Chad A., Luza, Sandra, Mancuso, Serafino G., Kang, Dali, Opazo, Carlos M., Mostaid, Md. Shaki, Cropley, Vanessa, McGorry, Patrick, Shannon Weickert, Cynthia, Pantelis, Christos, Bush, Ashley I., Everall, Ian P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381171/ https://www.ncbi.nlm.nih.gov/pubmed/30783160 http://dx.doi.org/10.1038/s41598-019-38490-1 |
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