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High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing

MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol that efficiently captures small RNAs while minimizing inherent biases associated with libr...

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Detalles Bibliográficos
Autores principales: Belair, Cassandra D., Hu, Tianyi, Chu, Brandon, Freimer, Jacob W., Cooperberg, Matthew R., Blelloch, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381177/
https://www.ncbi.nlm.nih.gov/pubmed/30783180
http://dx.doi.org/10.1038/s41598-018-38458-7