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High-throughput, Efficient, and Unbiased Capture of Small RNAs from Low-input Samples for Sequencing
MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol that efficiently captures small RNAs while minimizing inherent biases associated with libr...
Autores principales: | Belair, Cassandra D., Hu, Tianyi, Chu, Brandon, Freimer, Jacob W., Cooperberg, Matthew R., Blelloch, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381177/ https://www.ncbi.nlm.nih.gov/pubmed/30783180 http://dx.doi.org/10.1038/s41598-018-38458-7 |
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