Binding characterization of N‐(2‐chloro‐5‐thiomethylphenyl)‐N′‐(3‐[(3)H](3)methoxy phenyl)‐N′‐methylguanidine ([(3)H]GMOM), a non‐competitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist

Labeled with carbon‐11, N‐(2‐chloro‐5‐thiomethylphenyl)‐N′‐(3‐methoxyphenyl)‐N′‐methylguanidine ([(11)C]GMOM) is currently the only positron emission tomography (PET) tracer that has shown selectivity for the ion‐channel site of N‐methyl‐D‐aspartate (NMDA) receptors in human imaging studies. The pre...

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Detalles Bibliográficos
Autores principales: Metaxas, Athanasios, van Berckel, Bart N. M., Klein, Pieter J., Verbeek, Joost, Nash, Emily C., Kooijman, Esther J. M., Renjaän, Véronique A., Golla, Sandeep S. V., Boellaard, Ronald, Christiaans, Johannes A. M., Windhorst, Albert D., Leysen, Josée E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381215/
https://www.ncbi.nlm.nih.gov/pubmed/30784206
http://dx.doi.org/10.1002/prp2.458

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