Cargando…

Bayesian statistical learning for big data biology

Bayesian statistical learning provides a coherent probabilistic framework for modelling uncertainty in systems. This review describes the theoretical foundations underlying Bayesian statistics and outlines the computational frameworks for implementing Bayesian inference in practice. We then describe...

Descripción completa

Detalles Bibliográficos
Autores principales: Yau, Christopher, Campbell, Kieran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381359/
https://www.ncbi.nlm.nih.gov/pubmed/30729409
http://dx.doi.org/10.1007/s12551-019-00499-1
Descripción
Sumario:Bayesian statistical learning provides a coherent probabilistic framework for modelling uncertainty in systems. This review describes the theoretical foundations underlying Bayesian statistics and outlines the computational frameworks for implementing Bayesian inference in practice. We then describe the use of Bayesian learning in single-cell biology for the analysis of high-dimensional, large data sets.