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Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport
A series of fluorinated tripodal tris-thioureas function as highly active anion transporters across lipid bilayers and cell membranes. Here, we investigate their mechanism of action using anion transport assays in cells and synthetic vesicles and molecular modelling of transporter–lipid interactions...
Autores principales: | Spooner, Michael J., Li, Hongyu, Marques, Igor, Costa, Pedro M. R., Wu, Xin, Howe, Ethan N. W., Busschaert, Nathalie, Moore, Stephen J., Light, Mark E., Sheppard, David N., Félix, Vítor, Gale, Philip A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381411/ https://www.ncbi.nlm.nih.gov/pubmed/30881627 http://dx.doi.org/10.1039/c8sc05155k |
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