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Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer

OBJECTIVE: The co-incidence of lung cancer and coronary artery disease (CAD) is increasing in patients of advanced age. This study was performed to demonstrate the efficiency and safety of simultaneous coronary artery bypass grafting and lung cancer surgery in a selected group of older patients. MET...

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Autores principales: Li, Zhi, Liu, Ban, Ge, Wen, Zhang, Wei, Gu, Chang, Liu, Jingjing, Ke, Xianting, Zhang, Yangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381511/
https://www.ncbi.nlm.nih.gov/pubmed/30318969
http://dx.doi.org/10.1177/0300060518805297
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author Li, Zhi
Liu, Ban
Ge, Wen
Zhang, Wei
Gu, Chang
Liu, Jingjing
Ke, Xianting
Zhang, Yangyang
author_facet Li, Zhi
Liu, Ban
Ge, Wen
Zhang, Wei
Gu, Chang
Liu, Jingjing
Ke, Xianting
Zhang, Yangyang
author_sort Li, Zhi
collection PubMed
description OBJECTIVE: The co-incidence of lung cancer and coronary artery disease (CAD) is increasing in patients of advanced age. This study was performed to demonstrate the efficiency and safety of simultaneous coronary artery bypass grafting and lung cancer surgery in a selected group of older patients. METHODS: Twenty patients with severe CAD and coexisting lung cancer underwent simultaneous surgical interventions (Group A), and 20 patients with lung cancer underwent an isolated lung cancer operation (Group B). In Group A, the combined operations were carried out through 2 incisions in 3 patients, a single incision in 14 patients, and median sternotomy for heart surgery and thoracoscopic lobectomy for lung cancer in 3 patients. The single-incision approach was used in all patients in Group B. RESULTS: The operation time was longer and the blood loss volume was larger in Group A than B. No significant between-group differences were found in the 5-year relapse-free survival rate or 5-year survival rate. CONCLUSIONS: The simultaneous performance of lung cancer surgery and cardiac surgery was effective and evidently safe in Group A. This treatment approach enabled earlier lung cancer resection and avoidance of the eventual complications associated with further surgical procedures.
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spelling pubmed-63815112019-02-27 Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer Li, Zhi Liu, Ban Ge, Wen Zhang, Wei Gu, Chang Liu, Jingjing Ke, Xianting Zhang, Yangyang J Int Med Res Clinical Research Reports OBJECTIVE: The co-incidence of lung cancer and coronary artery disease (CAD) is increasing in patients of advanced age. This study was performed to demonstrate the efficiency and safety of simultaneous coronary artery bypass grafting and lung cancer surgery in a selected group of older patients. METHODS: Twenty patients with severe CAD and coexisting lung cancer underwent simultaneous surgical interventions (Group A), and 20 patients with lung cancer underwent an isolated lung cancer operation (Group B). In Group A, the combined operations were carried out through 2 incisions in 3 patients, a single incision in 14 patients, and median sternotomy for heart surgery and thoracoscopic lobectomy for lung cancer in 3 patients. The single-incision approach was used in all patients in Group B. RESULTS: The operation time was longer and the blood loss volume was larger in Group A than B. No significant between-group differences were found in the 5-year relapse-free survival rate or 5-year survival rate. CONCLUSIONS: The simultaneous performance of lung cancer surgery and cardiac surgery was effective and evidently safe in Group A. This treatment approach enabled earlier lung cancer resection and avoidance of the eventual complications associated with further surgical procedures. SAGE Publications 2018-10-14 2019-02 /pmc/articles/PMC6381511/ /pubmed/30318969 http://dx.doi.org/10.1177/0300060518805297 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Research Reports
Li, Zhi
Liu, Ban
Ge, Wen
Zhang, Wei
Gu, Chang
Liu, Jingjing
Ke, Xianting
Zhang, Yangyang
Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title_full Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title_fullStr Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title_full_unstemmed Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title_short Effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
title_sort effect of simultaneous surgical treatment of severe coronary artery disease and lung cancer
topic Clinical Research Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381511/
https://www.ncbi.nlm.nih.gov/pubmed/30318969
http://dx.doi.org/10.1177/0300060518805297
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