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Mitochondrial Role in Stemness and Differentiation of Hematopoietic Stem Cells

Quiescent and self-renewing hematopoietic stem cells (HSCs) rely on glycolysis rather than on mitochondrial oxidative phosphorylation (OxPHOS) for energy production. HSC reliance on glycolysis is considered an adaptation to the hypoxic environment of the bone marrow (BM) and reflects the low energet...

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Detalles Bibliográficos
Autores principales:	Papa, Luena, Djedaini, Mansour, Hoffman, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381553/ https://www.ncbi.nlm.nih.gov/pubmed/30881461 http://dx.doi.org/10.1155/2019/4067162

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