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Designing nutrition-based interventional trials for the future: addressing the known knowns
The consistent decline in critical illness mortality has a significant effect on trial design, whereby either an improbable effect sizes or large number of patients are required. The signal-to-noise ratio is of particular interest for the critically ill. When considering the potential signal, interv...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381615/ https://www.ncbi.nlm.nih.gov/pubmed/30782189 http://dx.doi.org/10.1186/s13054-019-2345-5 |