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Regulation of cyclin T1 during HIV replication and latency establishment in human memory CD4 T cells

BACKGROUND: The regulatory cyclin, Cyclin T1 (CycT1), is a host factor essential for HIV-1 replication in CD4 T cells and macrophages. The importance of CycT1 and the Positive Transcription Elongation Factor b (P-TEFb) complex for HIV replication is well-established, but regulation of CycT1 expressi...

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Detalles Bibliográficos
Autores principales:	Couturier, Jacob, Orozco, Aaron F., Liu, Hongbing, Budhiraja, Sona, Siwak, Edward B., Nehete, Pramod N., Sastry, K. Jagannadha, Rice, Andrew P., Lewis, Dorothy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381639/ https://www.ncbi.nlm.nih.gov/pubmed/30786885 http://dx.doi.org/10.1186/s12985-019-1128-6

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