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Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

BACKGROUND: Japanese cedar (JC) pollinosis is a serious type I allergic disease in Japan. Although subcutaneous immunotherapy and sublingual immunotherapy have been applied to treat JC pollinosis, high doses of allergens may cause IgE-mediated allergic reactions. The transgenic rice seeds that conta...

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Detalles Bibliográficos
Autores principales: Takaishi, Shinya, Saito, Saburo, Kamada, Minori, Otori, Nobuyoshi, Kojima, Hiromi, Ozawa, Kenjiro, Takaiwa, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381677/
https://www.ncbi.nlm.nih.gov/pubmed/30828418
http://dx.doi.org/10.1186/s13601-019-0249-8