Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression

BACKGROUND: Hepatocellular carcinoma (HCC) with stemness features are pivotal for tumorigenesis, chemoresistance, and progression. Long non-coding RNAs have been implicated in the regulation of HCC stemness features; however, their mechanisms remain largely unknown. Here, we found that Lnc-PDZD7 is...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Tang, Bo, Song, Jun, Yu, Shuiping, Li, Yang, Su, Huizhao, He, Songqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381703/
https://www.ncbi.nlm.nih.gov/pubmed/30786928
http://dx.doi.org/10.1186/s13046-019-1106-2

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