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Hypericin-photodynamic therapy inhibits the growth of adult T-cell leukemia cells through induction of apoptosis and suppression of viral transcription

BACKGROUND: Adult T-cell leukemia (ATL) is an aggressive neoplasm caused by human T-cell leukemia virus type 1 (HTLV-1). ATL carries a poor prognosis due to chemotherapy resistance. Thus, it is urgent to develop new treatment strategies. Hypericin (HY) is a new-type of photosensitizer in the context...

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Detalles Bibliográficos
Autores principales:	Xu, Lingling, Zhang, Xueqing, Cheng, Wenzhao, Wang, Yong, Yi, Kaining, Wang, Zhilong, Zhang, Yiling, Shao, Linxiang, Zhao, Tiejun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381730/ https://www.ncbi.nlm.nih.gov/pubmed/30782173 http://dx.doi.org/10.1186/s12977-019-0467-0

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