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Efficacy and safety of levothyroxine (L-T4) replacement on the exercise capability in chronic systolic heart failure patients with subclinical hypothyroidism: Study protocol for a multi-center, open label, randomized, parallel group trial (ThyroHeart-CHF)

BACKGROUND: Subclinical hypothyroidism is a common condition in patients with heart failure and is defined as elevated serum thyroid hormone (TSH) with normal circulating free thyroxine (FT4). Evidence on the effect of thyroid hormone treatment is lacking. We designed a randomized controlled trial t...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Wang, Wen-yao, Zhang, Kuo, Tian, Jian, Zheng, Ji-lin, Chen, Jing, An, Shi-min, Wang, Si-yuan, Liu, Yu-peng, Zhao, Yan, Wang, Jing-jia, Yang, Min, Tang, Yi-da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381733/
https://www.ncbi.nlm.nih.gov/pubmed/30782213
http://dx.doi.org/10.1186/s13063-019-3219-5