Cargando…

Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review

Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment op...

Descripción completa

Detalles Bibliográficos
Autores principales: Almuzayyen, Ahmed, Elhassan, Wahbi, Alabbadi, Mousa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381848/
https://www.ncbi.nlm.nih.gov/pubmed/30787858
http://dx.doi.org/10.4103/sjmms.sjmms_84_17
_version_ 1783396583127121920
author Almuzayyen, Ahmed
Elhassan, Wahbi
Alabbadi, Mousa
author_facet Almuzayyen, Ahmed
Elhassan, Wahbi
Alabbadi, Mousa
author_sort Almuzayyen, Ahmed
collection PubMed
description Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment options can be used as a single or combined approach. Prognosis depends on the extent of systemic involvement, and solitary lesions respond favorable to treatment. Here, the authors report a case of a 10-year-old male patient with Langerhans cell histiocytosis affecting his right posterior mandible that was successfully treated with intralesional injection of triamcinolone in multiple sessions. Complete recovery was confirmed clinically and radiographically in 18 months from the time of diagnosis.
format Online
Article
Text
id pubmed-6381848
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-63818482019-02-20 Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review Almuzayyen, Ahmed Elhassan, Wahbi Alabbadi, Mousa Saudi J Med Med Sci Case Report Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment options can be used as a single or combined approach. Prognosis depends on the extent of systemic involvement, and solitary lesions respond favorable to treatment. Here, the authors report a case of a 10-year-old male patient with Langerhans cell histiocytosis affecting his right posterior mandible that was successfully treated with intralesional injection of triamcinolone in multiple sessions. Complete recovery was confirmed clinically and radiographically in 18 months from the time of diagnosis. Medknow Publications & Media Pvt Ltd 2019 2018-12-14 /pmc/articles/PMC6381848/ /pubmed/30787858 http://dx.doi.org/10.4103/sjmms.sjmms_84_17 Text en Copyright: © 2018 Saudi Journal of Medicine & Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Almuzayyen, Ahmed
Elhassan, Wahbi
Alabbadi, Mousa
Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title_full Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title_fullStr Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title_full_unstemmed Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title_short Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
title_sort intralesional triamcinolone for treating mandibular langerhans cell histiocytosis: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381848/
https://www.ncbi.nlm.nih.gov/pubmed/30787858
http://dx.doi.org/10.4103/sjmms.sjmms_84_17
work_keys_str_mv AT almuzayyenahmed intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview
AT elhassanwahbi intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview
AT alabbadimousa intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview