Cargando…
Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review
Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment op...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381848/ https://www.ncbi.nlm.nih.gov/pubmed/30787858 http://dx.doi.org/10.4103/sjmms.sjmms_84_17 |
_version_ | 1783396583127121920 |
---|---|
author | Almuzayyen, Ahmed Elhassan, Wahbi Alabbadi, Mousa |
author_facet | Almuzayyen, Ahmed Elhassan, Wahbi Alabbadi, Mousa |
author_sort | Almuzayyen, Ahmed |
collection | PubMed |
description | Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment options can be used as a single or combined approach. Prognosis depends on the extent of systemic involvement, and solitary lesions respond favorable to treatment. Here, the authors report a case of a 10-year-old male patient with Langerhans cell histiocytosis affecting his right posterior mandible that was successfully treated with intralesional injection of triamcinolone in multiple sessions. Complete recovery was confirmed clinically and radiographically in 18 months from the time of diagnosis. |
format | Online Article Text |
id | pubmed-6381848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-63818482019-02-20 Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review Almuzayyen, Ahmed Elhassan, Wahbi Alabbadi, Mousa Saudi J Med Med Sci Case Report Langerhans cell histiocytosis is a rare condition ranging in manifestation from a focal boney lesion to multisystem involvement. Several treatment modalities have been proposed including curettage, low-dose radiotherapy, chemotherapy and intralesional injection of corticosteroids. These treatment options can be used as a single or combined approach. Prognosis depends on the extent of systemic involvement, and solitary lesions respond favorable to treatment. Here, the authors report a case of a 10-year-old male patient with Langerhans cell histiocytosis affecting his right posterior mandible that was successfully treated with intralesional injection of triamcinolone in multiple sessions. Complete recovery was confirmed clinically and radiographically in 18 months from the time of diagnosis. Medknow Publications & Media Pvt Ltd 2019 2018-12-14 /pmc/articles/PMC6381848/ /pubmed/30787858 http://dx.doi.org/10.4103/sjmms.sjmms_84_17 Text en Copyright: © 2018 Saudi Journal of Medicine & Medical Sciences http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Almuzayyen, Ahmed Elhassan, Wahbi Alabbadi, Mousa Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title | Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title_full | Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title_fullStr | Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title_full_unstemmed | Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title_short | Intralesional Triamcinolone for Treating Mandibular Langerhans Cell Histiocytosis: A Case Report and Literature Review |
title_sort | intralesional triamcinolone for treating mandibular langerhans cell histiocytosis: a case report and literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381848/ https://www.ncbi.nlm.nih.gov/pubmed/30787858 http://dx.doi.org/10.4103/sjmms.sjmms_84_17 |
work_keys_str_mv | AT almuzayyenahmed intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview AT elhassanwahbi intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview AT alabbadimousa intralesionaltriamcinolonefortreatingmandibularlangerhanscellhistiocytosisacasereportandliteraturereview |